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Botox for Excessive Sweating (Hyperhidrosis)

Beyond wrinkles, botulinum toxin has a well-established medical use: reducing excessive sweating. This guide explains how underarm (and other) hyperhidrosis treatment works.

6 min readUpdated June 2026
Abstract illustration of water droplets fading into a dry, fresh surface, representing Botox for excessive underarm sweating (hyperhidrosis).
Medically reviewed by Dr Kenneth Lee, Medical DirectorLast reviewed June 2026

What hyperhidrosis is

Hyperhidrosis means sweating far more than the body needs for temperature control. It can soak clothing, disrupt work and social life, and persist regardless of temperature or activity. It's a genuine medical issue — not a hygiene problem — and the underarms (axillae) are one of the most commonly affected and most treatable areas.

How botulinum toxin helps

Sweat glands are switched on by nerve signals using a chemical messenger. Botulinum toxin temporarily blocks that messenger at the treated area, so the overactive glands receive far fewer 'sweat' signals and produce much less sweat. It's the same medicine used for wrinkles, applied for a different, well-established purpose.

Treatment involves a series of small, shallow injections across the affected area after assessment.

How long it lasts

Sweat-reduction results commonly last longer than facial anti-wrinkle treatment — often several months and sometimes longer — before the glands gradually become active again and treatment can be repeated. As always, longevity varies by individual. Your doctor will give you a realistic range.

— Comparison

Sweat treatment vs facial anti-wrinkle — same medicine, different use

Target

Sweating (hyperhidrosis)
Overactive sweat glands
Facial anti-wrinkle
Movement (expression) muscles

Typical longevity

Sweating (hyperhidrosis)
Often several months or longer
Facial anti-wrinkle
Around 3–4 months

Why have it

Sweating (hyperhidrosis)
Medical — sweating affecting daily life
Facial anti-wrinkle
Cosmetic — softening dynamic lines

Who it may suit — and the medical check first

It may suit people whose excessive sweating hasn't responded well to strong antiperspirants and is affecting daily life. Because excessive sweating can occasionally signal an underlying condition, a doctor assesses your history first to make sure treatment is appropriate and to rule out other causes — this is a medical treatment, not a walk-in cosmetic one.

At DrPlus in Johor Bahru, hyperhidrosis is assessed individually; availability and suitability are confirmed at consultation.

— Frequently asked

Common questions

It temporarily blocks the nerve signal that tells sweat glands to produce sweat in the treated area, so overactive glands produce much less. It's the same medicine used for wrinkles, used here for a different, well-established purpose.

Often longer than facial anti-wrinkle treatment — commonly several months and sometimes more — before the glands gradually become active again and treatment can be repeated. Longevity varies by individual.

The underarms are the most common and treatable area. Palms and some other areas are sometimes treated too. A doctor assesses what's appropriate for you.

It's a recognised medical use of botulinum toxin, but because excessive sweating can occasionally point to an underlying condition, a doctor assesses your history first to confirm it's appropriate and rule out other causes.

— Related treatments

Each page goes deeper into mechanism, suitability and recovery — your final plan is confirmed at consultation.

— Continue reading