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DrPlus Skin Education · Singapore

Rejuran Skin Booster in Singapore: PN, PDRN & Salmon DNA

Rejuran is a polynucleotide skin booster, not a filler. This guide explains PN, PDRN and salmon-DNA phrasing, the usual course, and when another family fits better.

8 min readUpdated Aug 2026
Rejuran polynucleotide skin booster treatment at DrPlus Singapore
Medically reviewed by Dr Kenneth Lee, Medical DirectorLast reviewed Aug 2026
Considering treatment? See Rejuran skin booster treatment in Singapore.

What a Rejuran skin booster actually is

Rejuran — often searched as 'rejuran skin booster' or Rejuran Healer — is an injectable based on polynucleotides (PN), DNA fragments purified from salmon and prepared for medical use. It is not designed to add cheek or lip volume. The intended job is to support the skin's own repair environment: fine texture, thin or tired-looking skin, barrier recovery, and quality changes that build across a course.

That is why clinics describe it as a skin healer rather than a hydrator. Classic HA boosters hold water where the droplets sit. Profhilo spreads high-concentration HA to bio-remodel. Rejuran is the repair-shaped tool in that set. Choosing it because a friend liked the glow, when your actual problem is laxity or dehydration alone, is how a full course still misses the concern.

The session course — why one visit is not the treatment

Most Rejuran protocols run three to four sessions spaced a few weeks apart, then maintenance if you and your doctor decide the response justifies it. Thin, textured or stressed skin often needs the full course before anyone can judge the result fairly.

The injections are many small points across the mapped area. Numbing cream is used. Small bumps and redness are common for one to three days — longer than Profhilo's few-point pattern for many patients. 'Glass skin booster' is a marketing nickname for the finish some people hope for; it does not mean poreless, filter-like skin.

— Pathway

A typical Rejuran journey

  1. 01

    Assessment

    The doctor checks whether repair is the actual job — or whether HA, Profhilo or a non-injectable pathway fits better.

  2. 02

    Course

    Several sessions, spaced weeks apart, with the same mapped area reviewed each visit.

  3. 03

    Review

    Quality change is judged across the course, then a maintenance cadence is set only if it is earning its place.

Rejuran versus Profhilo versus a classic HA booster

If the complaint is early laxity, crepiness or tired-looking quality, bio-remodelling is usually the first conversation. If it is post-acne texture, sensitivity-prone or damaged skin, or fine crepe under the eyes, polynucleotides come forward. If it is dryness and dullness, a classic HA booster does that job more directly.

Combinations can be staged over a year. Stacking Rejuran and Profhilo in one visit because both are popular is usually the expensive way to stay confused. Complete one well-chosen course and review it.

Rejuran consultations in Singapore

At Tanjong Pagar, East Coast and Novena, Rejuran is one option in a skin-quality toolkit — not the default sale. You receive a written protocol and full-course cost before anything is booked. Results vary by individual.

— Frequently asked

Common questions

Rejuran is based on polynucleotides (PN) derived from salmon DNA and purified for medical use. It is injected to support skin repair and quality — not to add facial volume.

PDRN is a related class of DNA-derived injectable. Rejuran is a specific PN product patients in Singapore search by name. Your doctor will say which licensed product, if any, fits — the search term is not the prescription.

A course of several sessions spaced a few weeks apart is common, followed by maintenance depending on response. Your doctor proposes the count at assessment and reviews progress as the course proceeds.

They do different jobs: Rejuran is repair-focused; Profhilo is a high-concentration HA bio-remodeller. The fit depends on your skin, which is what the consultation assesses.

DrPlus offers doctor-led Rejuran consultations at SBF Center in Tanjong Pagar, The Flow Mall on East Coast Road, and Novena Medical Centre. Suitability is confirmed before a course is priced.

— Related treatments

Each page goes deeper into mechanism, suitability and recovery — your final plan is confirmed at consultation.

— Continue reading