Tanjong Pagar / CBD
SBF Center
Dr Plus Aesthetics Clinic Singapore (Tanjong Pagar)
160 Robinson Road #03-10
Singapore 068914
About a three-minute walk from Tanjong Pagar MRT (East–West Line); the building has a carpark.
Doctor-Led Clinic
DrPlus Singapore · Aesthetic
Rejuran Skin Booster in Singapore
A polynucleotide (PN/PDRN) skin healer for texture, fine lines and fragile skin — not a filler. A doctor at Tanjong Pagar, East Coast or Novena maps whether Rejuran, Profhilo or another family fits. WhatsApp a photo of your skin for an honest first answer — no obligation.
- Doctor-performed injections
- Written quote after assessment
- No obligation to proceed
Medically reviewed by Dr Kenneth Lee, Medical DirectorLast reviewed October 2026Last updated 19 October 2026MBBCh (Cardiff University), GDipFP Dermatology (NUS)
— Who this page is for
Who this page is for
Rejuran attracts patients focused on skin repair and quality rather than volume. Whether it suits your skin — or whether another injectable fits better — is decided at consultation.
Concerned about skin quality
Fine lines, dullness, or thinning skin texture bother you and you want a repair-focused treatment rather than volume or filler.
Comparing Rejuran with Profhilo
You have read about both and want a doctor's explanation of how they differ and which suits your skin — not a sales pitch for either.
Interested in acne-scar support
You have heard Rejuran discussed for acne scarring and want an honest assessment of where it fits alongside other scar treatments.
Preferring gradual, natural change
You want your skin to improve in quality over weeks, without an obvious 'had work done' look.
— What this involves
What Rejuran treatment involves
Rejuran — often searched as a Rejuran skin booster — is an injectable treatment based on polynucleotides (PN) derived from salmon DNA, often described as a 'skin healer'. Rather than adding volume like a filler, it aims to support the skin's own repair processes — targeting skin quality, elasticity, and fine lines. Results develop gradually and vary by individual.
Many patients arrive comparing Rejuran with Profhilo. They are different products with different mechanisms — polynucleotide-based repair versus hyaluronic-acid-based hydration — and the better fit depends on your skin condition and goals. Your doctor will explain the comparison plainly at consultation, and our education article on Profhilo vs Rejuran is a useful starting point.
Treatment is typically planned as a short course of sessions spaced weeks apart, followed by review. The injections involve multiple small points across the treatment area; numbing cream is used for comfort, and small bumps or redness at injection points usually settle within a day or two.
Suitability is assessed first — skin condition, history, and what you want to change. A personalised plan and written quote follow the consultation, with no obligation to proceed.
— What to expect on the day
Your Rejuran appointment, step by step
A first visit combines the consultation and, if appropriate, the first session of the course. You can also take the plan away and decide later.
— What to expect
What a Rejuran plan at DrPlus involves
A short course, many small injection points, and a review — you know the session count before anything is booked.
WhatsApp enquiry
Send your concern — a photo helps. A doctor can usually say whether a repair-focused conversation is worth a clinic visit, or whether Profhilo or an HA booster is the closer family.
Doctor consultation
Texture, barrier condition and thin or stressed skin are examined at Tanjong Pagar, East Coast or Novena. If Rejuran is not the fit, you hear that before a course is priced.
Course of sessions
Several visits spaced a few weeks apart are common. Numbing cream is used; many micro-injections across the mapped area. You leave with written, product-specific aftercare.
Review
Quality change is judged across the course, not after the first visit. Maintenance is set only if the response justifies it.
What the hours after look like
Same day
A field of small bumps and mild redness is common. This is expected with a multi-point pattern.
Next 1–3 days
Bumps typically settle within one to three days — often a little longer than Profhilo's few-point pattern. Makeup is usually fine once the skin is closed.
Across the course
Repair-focused change is gradual and cumulative. Judge the result after the planned sessions, not the morning after visit one.
Timelines vary by individual and by area. Your doctor will brief you on the pattern that applies to your plan.
— Aftercare
Rejuran aftercare: the first days
The small bumps after Rejuran are expected and usually flatten within one to three days. Simple precautions help the skin settle; your written aftercare sheet confirms the details for your plan.
- Avoid makeup on the treated area until the injection points have closed, usually the next day.
- Avoid saunas, hot baths, strenuous exercise and alcohol for the first day or two.
- Do not rub or massage the bumps; let them settle on their own.
- Use a gentle cleanser and moisturiser, and daily sunscreen.
- Avoid facials, peels and laser treatments on the area for about a week unless your doctor plans otherwise.
— Risks & side effects
Is Rejuran safe? Risks and side effects
Rejuran is generally well tolerated when a doctor assesses you first and injects a registered product. Most side effects are mild and short-lived, but no injection is risk-free, and your doctor explains the risks before you decide.
- Expected: a pattern of small raised bumps, redness and mild swelling at injection points, usually settling within one to three days.
- Common: small bruises and tenderness, especially around the eyes or if you take blood thinners, fish oil or certain supplements.
- Uncommon: bumps that last longer than expected, temporary unevenness, or infection at an injection site. Contact the clinic if the area becomes hot, painful or increasingly swollen.
- Rare: allergic reaction. Rejuran is salmon-derived, so a fish or salmon allergy must be mentioned at consultation.
- Not suitable during pregnancy or breastfeeding, with active infection, acne flare or cold sores in the area, or with a known allergy to an ingredient.
— Choosing a doctor
How to choose a doctor for Rejuran in Singapore
Rejuran is widely offered, so it helps to ask about the product, the plan and who injects. These questions are reasonable at any clinic, including ours.
- Is a registered doctor assessing you and injecting? Any doctor can be looked up on the Singapore Medical Council's online register.
- Is the product genuine Rejuran registered with the Health Sciences Authority, and will the doctor name the formulation?
- Did the doctor explain why Rejuran suits your concern better than Profhilo or a hyaluronic acid booster — or say if it does not?
- How many sessions does the course need, how far apart, and what does maintenance look like?
- Is there a clear plan if you have a reaction or bumps that do not settle?
- Do you receive a written plan after assessment, with time to decide?
— Compared with alternatives
Rejuran compared with Profhilo, HA boosters and other options
Rejuran is one of several skin-quality injectables. The table shows what each is designed for, which is the clearest way to see why a doctor might suggest Rejuran, another option or a combination.
| Option | Designed for | Typical course |
|---|---|---|
| Rejuran (polynucleotides) | Repair, fine texture, fragile or post-acne skin, under-eye skin | Three to four sessions, then maintenance |
| Profhilo | Firmness and overall skin quality, crepey skin | Two sessions about a month apart, then maintenance |
| Hyaluronic acid skin boosters | Hydration, fine dry lines and glow | Two to three sessions, then maintenance |
| Dermal fillers | Lost volume and contour | Usually one session; lasts months to over a year |
| Lasers and microneedling | Acne scars, pores and surface texture | A series of sessions; no injection |
— Why DrPlus
How we plan Rejuran in Singapore
Honest product selection at Tanjong Pagar, East Coast or Novena — we recommend the injectable that fits your skin, not the one that is easiest to sell.
Doctor-performed treatment
Assessment and injections are carried out by a qualified physician using authentic, properly sourced product.
Unbiased product comparison
Rejuran, Profhilo, and skin boosters are compared on your skin's needs — you will hear which fits and why.
Course planned with review
Sessions are planned as a reviewed course so progress is tracked, rather than sold open-endedly.
Realistic expectations
Skin-quality change is gradual and individual — we set expectations honestly before you commit.
Ready to discuss your skin?
Book a doctor-led assessment tailored to your concerns.
— Cost factors
What determines Rejuran cost in Singapore
We do not publish prices. Rejuran is a multi-session course, so a one-visit figure hides the real number. After assessment you receive a written, personalised quote in Singapore dollars — no obligation to proceed.
WhatsApp us first if you want to understand what would shape your quote before you visit Tanjong Pagar, East Coast or Novena.
- How many sessions complete the initial course — commonly several, spaced weeks apart
- Treatment area — face, under-eye, or a mapped zone
- Product variant and volume your doctor actually plans
- What is bundled — numbing, review visits, and who injects
— Related treatments
Related skin-quality treatments
Rejuran is most often weighed against other skin-quality injectables. These resources help you compare before your consultation.
01
Rejuran Skin Booster Guide
Suited to: PN, PDRN and the usual courseThe Singapore education article this page is built for — what Rejuran is, and when another family fits better.
Learn More02
Profhilo vs Rejuran vs HA
Suited to: Educational comparisonHow polynucleotide repair differs from Profhilo bio-remodelling and classic HA hydration.
Learn More03
Skin Boosters
Suited to: Hydration & glowHyaluronic-acid-based injectable hydration — sometimes the better fit when dryness and dullness are the main concern.
Learn More04
Profhilo
Suited to: Bio-remodelling hydrationThe high-concentration HA bio-remodelling treatment most often compared with Rejuran — see how it works.
Learn More05
Skin Booster Cost in Singapore
Suited to: Course pricing, not a jabWhat moves a Rejuran or Profhilo quote — sessions, family and what to compare between clinics.
Learn More— Our Singapore clinics
Three Singapore clinics, one doctor-led standard
Consultations and treatments are available at all three clinics — choose whichever is more convenient: the Tanjong Pagar CBD, Katong on the East Coast, or the Novena medical district.
East Coast / Katong
The Flow Mall
Dr Plus Aesthetics Clinic (East Coast)
66 East Coast Road #03-05
Singapore 428778
A short walk from Marine Parade MRT (Thomson–East Coast Line); The Flow Mall has a carpark.
Novena
Novena Medical Centre
Dr Plus Aesthetics Clinic (Novena)
10 Sinaran Drive #10-30
Singapore 307506
A short sheltered walk from Novena MRT (North–South Line); Novena Medical Centre has a carpark.
— FAQ
Common questions
Rejuran is based on polynucleotides (PN) derived from salmon DNA, purified for medical use. It is injected into the skin with the aim of supporting the skin's own repair processes — which is why it is often described as a 'skin healer' rather than a filler.
They work differently: Rejuran is polynucleotide-based and repair-focused, while Profhilo is a high-concentration hyaluronic acid treatment focused on hydration and skin laxity. The right choice depends on your skin condition and goals, which is exactly what the consultation assesses. Our Singapore comparison of Profhilo, Rejuran and HA boosters covers the difference in detail.
A course of several sessions spaced a few weeks apart is common, followed by maintenance depending on response. Your doctor will propose a plan at consultation and review progress as the course proceeds — response varies by individual.
It depends on the skin concern, the formulation, and how your skin responds. Most plans start with a course, then maintenance sessions months apart — Rejuran is not a one-off permanent change. Your doctor sets the review interval after seeing the response. There is no single duration that applies to everyone.
The treatment involves multiple small injections, so numbing cream is applied beforehand. Most patients describe it as tolerable, with small bumps or redness at the injection points that typically settle within a day or two.
We do not publish prices — the quote depends on the product variant, treatment area, and number of sessions planned. You will receive a personalised written quote after your skin assessment, with no obligation to proceed.
It is often grouped with skin boosters because both are injected to improve skin quality rather than add volume — but the mechanism differs. Most skin boosters are hyaluronic-acid-based and hydrate; Rejuran is polynucleotide-based and repair-focused. Some patients suit one, some the other, and some a planned sequence — which is exactly what the doctor assesses at consultation.
Both terms describe the same salmon-DNA-derived ingredient family. PDRN (polydeoxyribonucleotide) is the shorter-fragment form; PN (polynucleotide) is the longer-chain form used in Rejuran Healer, which is why Rejuran is described as a PN booster but turns up in nearly every 'PDRN skin booster' search. The clinical point is the same: a repair-focused booster for post-acne texture, fine lines and fragile skin, rather than a hydration-first HA booster. Your doctor confirms which Rejuran formulation — if any — fits your skin at consultation.
We see patients at SBF Center, 160 Robinson Road #03-10, in the Tanjong Pagar CBD (call +65 8851 9547), The Flow Mall, 66 East Coast Road #03-05, in Katong on the East Coast (call +65 8857 4917), and Novena Medical Centre, 10 Sinaran Drive #10-30, in Novena (call +65 8851 9505). All three clinics offer the same doctor-led consultations, so you can choose whichever location is more convenient.
SBF Center on Robinson Road is about a three-minute walk from Tanjong Pagar MRT (East–West Line) in the CBD, The Flow Mall on East Coast Road in Katong is a short walk from Marine Parade MRT on the Thomson–East Coast Line, and Novena Medical Centre on Sinaran Drive is a short sheltered walk from Novena MRT on the North–South Line. If you drive, all three buildings have carparks, with further public parking nearby.
— Request a Consultation
Find out if Rejuran fits — before you commit
WhatsApp a photo of your concern, or send the form below. A doctor maps Rejuran, Profhilo or another family to your skin, and you receive a written plan only if a course is justified. No obligation.
- Doctor-led assessment and recommendations
- Singapore clinics at Tanjong Pagar, East Coast and Novena
- Reviewed personally — not auto-routed
- Reply via WhatsApp, typically within one business day
Doctor-Led
Personalised Plans
Reply within 24 hrs
— Skin Education
Related Skin Education
Doctor-led guides written to help you understand your options before consultation. Each article links back to the relevant treatment pages.
Skin BoostersPDRN & PN Skin Boosters: Rejuran & Plinest
PN and PDRN are often used interchangeably online. This clinical guide clarifies the terms and compares Rejuran and Plinest without promising outcomes.
9 min readRead article
Skin BoostersProfhilo vs Rejuran vs Skin Boosters: A Singapore Guide
Three injectable 'skin quality' treatments, three different mechanisms. This guide separates bio-remodelling, polynucleotide repair and micro-droplet hydration so you can match the tool to your skin.
8 min readRead article
Skin BoostersWhat Is a Skin Booster Injection? A Singapore Guide
Injectable skin boosters improve skin quality from within. This guide separates medical boosters from retail serums, and HA, Profhilo and Rejuran from each other.
10 min readRead article
Skin BoostersHow Much Do Skin Boosters Cost in Singapore? What Shapes the Quote
Skin boosters are course-based treatments, so single-session prices mislead. This guide explains the protocols behind Profhilo, Rejuran and HA boosters — and how their costs really compare.
7 min readRead article
Skin BoostersExosome Skin Boosters vs HA, Profhilo & Rejuran: A Singapore Guide
Exosome skin booster is a high-volume search. This guide explains the difference from classic boosters and why DrPlus Singapore plans HA, Profhilo and Rejuran — not an exosome menu.
7 min readRead article
Skin BoostersKorean Skin Boosters in Singapore: NCTF, Chanel & What the Names Mean
Korean skin booster, NCTF and Chanel are search terms, not one licensed product. This guide translates the slang and explains why unregistered cocktails are a safety issue.
8 min readRead article
Profhilo vs Rejuran: How to Choose
Two of the most asked-about injectable skin treatments — and they are not interchangeable. Here is how a doctor actually decides between them.
9 min readRead article
— Methods compared
The Rejuran range — what each variant targets
Rejuran is a family of polynucleotide products, not a single injectable. The variants differ in formulation and target area — which one (if any) fits your skin is a consultation decision, not a menu choice.
The original
Rejuran Healer
The standard polynucleotide formulation most people mean by 'Rejuran' — repair-focused treatment for overall skin quality.
- Full-face skin quality, texture and fine lines
- Planned as a short course with review
Hydro booster
Rejuran HB
Polynucleotides blended with hyaluronic acid — leans further toward hydration alongside repair.
- Dry, dull skin where hydration is a co-goal
- Sits between Healer and an HA skin booster
Eye formulation
Rejuran I
A thinner formulation designed for the delicate under-eye area.
- Fine lines and crepey texture around the eyes
- Injected superficially with a fine technique
Scar formulation
Rejuran S
A thicker formulation used on depressed scars, usually within a wider scar plan.
- Selected acne scars alongside subcision or lasers
- Scar mapping comes first — it is not a standalone fix
The doctor at Tanjong Pagar, East Coast or Novena confirms which variant your skin actually needs — and says honestly if a different family (Profhilo, HA skin boosters) is the closer fit.
Medical disclaimer
Information on this page is for general education only and does not replace a consultation with a qualified medical practitioner. Suitability, downtime, risks, and results vary by individual. Please consult your doctor before deciding on any treatment. Read the full medical disclosure.
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